Sample size estimation for Prescott's test
in [SAS]
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From: David L Cassell on 6 Apr 2007 01:36 Madan.Kundu(a)RANBAXY.COM wrote: > >Dear ALL, > >Currently I am concentrating in planning of a 2x2 cross-over trial with >binary response (preference - 0: Good; 1: Bad). And in this case I think >Prescott's test would be an automatic choice. Now I wonder how to >calculate required sample size for this trial so that we can meet the >trial objective. > >I would be highly thankful to you if you let me know the way in which >sample size can be calculated for a trial where efficacy analysis is >based on Prescott's test. > >With best regards >Madan Gopal Kundu I don't know how you can get a required sample size for Prescott's test. That would require that you be able to quantify something about the eventual table structure before you run the experiment. Instead, use Prescott's test, but focus on a sample size for McNemar's test or Maitland-Gart. You should be able to use PROC POWER to help you there. HTH, David -- David L. Cassell mathematical statistician Design Pathways 3115 NW Norwood Pl. Corvallis OR 97330 _________________________________________________________________ Need a break? Find your escape route with Live Search Maps. http://maps.live.com/?icid=hmtag3
From: Madan Gopal Kundu on 6 Apr 2007 06:09 Thank you very much David. Regards MADAN -----Original Message----- From: SAS(r) Discussion [mailto:SAS-L(a)LISTSERV.UGA.EDU] On Behalf Of David L Cassell Sent: 06 April 2007 11:06 To: SAS-L(a)LISTSERV.UGA.EDU Subject: Re: Sample size estimation for Prescott's test Madan.Kundu(a)RANBAXY.COM wrote: > >Dear ALL, > >Currently I am concentrating in planning of a 2x2 cross-over trial with >binary response (preference - 0: Good; 1: Bad). And in this case I think >Prescott's test would be an automatic choice. Now I wonder how to >calculate required sample size for this trial so that we can meet the >trial objective. > >I would be highly thankful to you if you let me know the way in which >sample size can be calculated for a trial where efficacy analysis is >based on Prescott's test. > >With best regards >Madan Gopal Kundu I don't know how you can get a required sample size for Prescott's test. That would require that you be able to quantify something about the eventual table structure before you run the experiment. Instead, use Prescott's test, but focus on a sample size for McNemar's test or Maitland-Gart. You should be able to use PROC POWER to help you there. HTH, David -- David L. Cassell mathematical statistician Design Pathways 3115 NW Norwood Pl. Corvallis OR 97330 _________________________________________________________________ Need a break? Find your escape route with Live Search Maps. http://maps.live.com/?icid=hmtag3 (i) The information contained in this e-mail message is intended only for the confidential use of the recipient(s) named above. This message is privileged and confidential. If the reader of this message is not the intended recipient or an agent responsible for delivering it to the intended recipient, you are hereby notified that you have received this document in error and that any review, dissemination, distribution, or copying of this message is strictly prohibited. If you have received this communication in error, please notify us immediately by e-mail, and delete the original message. (ii) The sender confirms that Ranbaxy shall not be responsible if this email message is used for any indecent, unsolicited or illegal purposes, which are in violation of any existing laws and the same shall solely be the responsibility of the sender and that Ranbaxy shall at all times be indemnified of any civil and/ or criminal liabilities or consequences there.
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